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NFL Nation reporters assess the biggest injuries across the league for Week 3.

Scan through all 32 teams by division, or click here to jump ahead to your team:

AFC EAST

Buffalo Bills

Running back LeSean McCoy (cracked rib cartilage) and wide reciver Kelvin Benjamin (hip) were both limited in practice Wednesday. McCoy wore a non-contact jersey and said he would decide by Friday or Saturday whether he is able to run full speed without pain in Sunday’s game at Minnesota. If he cannot play, Marcus Murphy and Chris Ivory would likely split carries. McDermott said Benjamin had a “little bit of a hip” that did not seem to obviously hamper him when reporters were at practice Wednesday. — Mike Rodak

Miami Dolphins

Safety Reshad Jones suffered a right shoulder injury Sunday and missed practice on Wednesday. The good news is it isn’t the same left shoulder that he had surgery on in 2016. Adam Gase considers Jones “day-to-day” and he’s hoping Jones progresses enough to play on Sunday vs. Raiders. DeVante Parker was a full participant in practice again Wednesday, and is expected to make his season debut Sunday. Gase held him out one more week to be safe as Parker recovers from a broken middle finger. — Cameron Wolfe

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New England Patriots

Starting safety Patrick Chung and starting defensive end Trey Flowers both left Sunday’s loss in Jacksonville with concussions, and they didn’t practice on Wednesday. Given the often unpredictable nature of concussion recoveries, the Patriots have to plan being without them, while starting right tackle Marcus Cannon is still being held back by a calf strain and might need more time. Chung’s value to the Patriots was summed up by coach Bill Belichick, who said, “We’re fortunate that we have one Pat Chung. To have two Pat Chung’s would be pretty much impossible, so it would be multiple people to do all the things that he does.” — Mike Reiss

New York Jets

Saftey Marcus Maye (foot) is not expected to play Thursday night, which will be his third straight game on the sideline. Once again, Doug Middleton will start for Maye, whose injury is more serious than initially reported. The pass defense has held up well in his absence. — Rich Cimini

AFC NORTH

Baltimore Ravens

Running back Alex Collins missed Wednedsay’s practice with an illness. If this was serious, Baltimore would’ve likely made a move to add another running back. The only healthy back with experience is Javorius Allen. The bigger concern is the run defense. Middle linebacker C.J. Mosley (knee) is likely out Sunday, and defensive tackle Michael Pierce (foot) didn’t practice Wednesday, which leaves Baltimore with four healthy defensive linemen. That could prove a problem against Denver and the NFL’s No. 2 rushing attack. — Jamison Hensley

Cincinnati Bengals

Center Billy Price is in a walking boot with a foot injury that will be reevaluated in two weeks, meaning Trey Hopkins will take his spot. But it’s a mystery who will take Hopkins’ place if he goes down. Guard Clint Boling could be a candidate to move over in an emergency. Meanwhile, running back Giovani Bernard is prepared to shoulder the workload for Joe Mixon, who had a procedure done on his knee and is out for at least two weeks. Mixon said his timetable to return is essentially when he feels comfortable running and making cuts again without pain. — Katherine Terrell

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Bernard a must-add in Week 3Mike Clay details why Giovani Bernard is a pickup this week and where he sits in his RB rankings.

Cleveland Browns

Defensive end Emmanuel Ogbah will miss his second game, and linebacker Chris Kirksey is doubtful, which means the defense will be without its second-best pass rusher and best overall linebacker. The defense played well without them when facing Drew Brees on Sunday; it may find the same success against rookie QB Sam Darnold on Thursday. — Pat McManamon

Pittsburgh Steelers

Guard David DeCastro is in danger of missing his second straight game with a fractured hand that hasn’t fully healed. Teammate Alejandro Villanueva said DeCastro will be fine after leaving the practice field in pain Wednesday. But corner Joe Haden (hamstring) should be available for Monday Night Football against the Bucs. The hamstring is no longer a major issue, as Haden looks to practice in full this week. — Jeremy Fowler

AFC SOUTH

Houston Texans

Jadeveon Clowney (back) was again a limited participant in the Texans’ Wednesday practice. The defensive end missed Sunday’s loss to the Titans with the injury, and head coach Bill O’Brien said it’s too early in the week to know whether Clowney will play in Week 3. — Sarah Barshop

Indianapolis Colts

Take your choice: Receiver T.Y. Hilton (quad), tight end Jack Doyle (hip), running back Marlon Mack (foot/hamstring) or safety Clayton Geathers (knee/elbow). All four players did not practice Wednesday. Hilton is the biggest concern for the Colts, because he leads the team in receptions (12) and receiving yards (129). Durability has been a strongsuit of Hilton, as he has only missed two games in his six-plus years in the NFL. — Mike Wells

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Jacksonville Jaguars

Running back Leonard Fournette (hamstring) returned to practice for the first time since getting hurt in the season opener, and that’s good news for his chances of playing on Sunday. Losing left taclke Cam Robinson to a torn left ACL was a blow, but the team believes they’ll be okay with fourth-year player Josh Wells stepping in as the starter. Still, expect the Jaguars to give him help — a tight end lined up next to him or backs chipping, for example — against Titans pass-rusher Brian Orakpo on Sunday. Two of Orakpo’s seven sacks last season came against the Jaguars. — Michael DiRocco

Tennessee Titans

The biggest injury question mark for the Titans involves quarterback Marcus Mariota (elbow). Mariota is experiencing tingling in two of the fingers on his right hand. The discomfort is keeping him from gripping the ball, though he seemed to be more comfortable throwing during the open portion of practice on Wednesday. Head coach Mike Vrabel said he is going to monitor the situation and make a decision at the end of the week. Vrabel indicated that he is comfortable going with backup Blaine Gabbert if he has to. — Turron Davenport

AFC WEST

Denver Broncos

Quarterback Case Keenum on knee soreness that kept him out of Wednesday’s practice: “I woke up Monday a little sore, so I could have practiced today, I wanted to practice, but they wouldn’t let me … Come back and be ready to go (Thursday).” Chad Kelly worked with the starting offense Wednesday, including the team’s walk-through. Keenum reiterated, however, he expects to practice the remainder of the week and play Sunday in Baltimore. Meanwhile, cornerback Adam Jones (thigh), linebacker Brandon Marshall (knee) and tackle Jared Veldheer (concussion) did not practice on Wednesday. Coach Vance Joseph said he was “hopeful” Jones and Marshall would be ready to play Sunday in Baltimore. Veldheer is in the concussion protocol, and Joseph said the OT has not yet been cleared for additional activity. It was the first practice of the season the Broncos have had any players held out due to injuries. — Jeff Legwold

Kansas City Chiefs

Safety Eric Berry looks to be at least another week away from playing after he missed practice on Wednesday. The defense took another hit when its most versatile lineman, Chris Jones, sat out practice because of a groin strain. Not having Jones would be a problem on Sunday against the 49ers. The Chiefs don’t have much depth on the defensive line, and Jones has played in more snaps this season than any of their other linemen. — Adam Teicher

Los Angeles Chargers

Wide receiver Travis Benjamin was a game-time decision not to play last week against the Bills due to a foot injury. However, the Miami product was a limited participant in practice on Wednesday, an indication that the Chargers could have their speedy receiver available when they face one of the top defenses in the league in the Battle of Los Angeles on Sunday. — Eric D. Williams

Oakland Raiders

Rookie defensive tackle P.J. Hall is not expected to play in Miami this weekend, as the second-round draft pick continues to rehab his injured left ankle. Hall was injured in the season opener against the Rams and missed last weekend’s game at Denver. The Raiders had to put nose tackle Justin Ellis on injured reserve with a foot injury last week, and signed a pair of defensive tackles, in Clinton McDonald and Johnathan Hankins. McDonald responded with two pressures in 32 pass-rush snaps in Denver, per Pro Football Focus. — Paul Gutierrez

NFC EAST

Sean Lee did not practice Wednesday because of a hamstring injury that cropped up late in the win against the Giants, raising some question to his availability this week. He could have returned to the game if necessary, according to Jason Garrett, but the coaches opted to hold him out. The Cowboys went 1-4 in the five games Lee missed last season with hamstring strains, but they feel they are better protected at linebacker with the additions of Leighton Vander Esch and Joe Thomas this season. Lee was on the field during the portion of practice open to the media Wednesday. — Todd Archer

New York Giants

Outside linebacker Olivier Vernon (ankle) and cornerback Eli Apple (groin) didn’t practice Wednesday. Apple said he’s still sore and Vernon has already missed the first two games of the season. Both are in doubt for Sunday. — Jordan Raanan

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Philadelphia Eagles

Two of the Eagles’ top running backs, Jay Ajayi (back) and Darren Spoles (hamstring), missed practice Wednesday. Coach Doug Pederson called both day-to-day, but suggested Ajayi is closer to a return. The read here is that Sproles is in jeopardy of missing another week, while Ajayi’s status will be decided closer to game day. Corey Clement had 85 total yards and a touchdown against the Bucs, and should continue to see a boost in production with his backfield partners ailing. — Tim McManus

Washington Redskins

Left guard Shawn Lauvao has a bad calf that could force him to miss a few games, coach Jay Gruden said. Lauvao has missed 22 games combined the past three years because of injuries, going on injured reserve with a neck injury for the final seven games of 2017. If Lauvao, who struggled vs. the Colts last week, doesn’t play then starting center Chase Roullier will move to left guard, while Tony Bergstrom will start at center. The Redskins did not do an adequate job of addressing their interior depth, and it could cost them early as right guard Brandon Scherff also is dealing with a knee issue. — John Keim

NFC NORTH

Chicago Bears

The Bears head into their Week 3 matchup with the Cardinals remarkably healthy. Safety DeAndre Houston-Carson, who is recovering from a broken forearm, was the only player who did not practice on Wednesday. It seems the Bears’ only issue on the health front is getting Khalil Mack and Roquan Smith into better game shape after both went through holdouts. ESPN.com staff

Detroit Lions

As expected after suffering a concussion Sunday against San Francisco, cornerback Darius Slay didn’t practice Wednesday. That the Lions re-signed DeShawn Shead is also a sign that the All-Pro might not be ready for the Patriots — which has to be concerning for Detroit’s ability to handle outside receivers (particularly if Josh Gordon ends up playing). It’s going to bear watching the rest of the week, since concussions are hard to predict. Detroit did get some better news in that defensive end Ezekiel Ansah (shoulder) and offensive lineman T.J. Lang (back) participated on a limited basis. The Lions could use the two veterans against one of the NFL’s top teams. Returner Jamal Agnew (shoulder) was also limited, but no reason at this point to think he won’t be available. — Michael Rothstein

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Green Bay Packers

The Packers’ pass defense struggled after cornerback Kevin King dropped out of Sunday’s game against the Vikings because of a groin injury. It sounds like they’ll have to figure out a way to play without him this week against the Redskins. Coach Mike McCarthy said King would be “hard-pressed” to play this week, although he does not believe it’s a long-term injury. — Rob Demovsky

Minnesota Vikings

For the first time since the 2017 postseason, Pat Elflein was listed as a full participant on the injury report. If the second-year center continues to practice in full on Thursday and Friday, there’s a possibility he returns in Week 3 against Buffalo. Running back Dalvin Cook sustained a hamstring injury in Week 2 that he equated to a “cramp,” but it appears to be more than that as it kept him out of practice three days later. Cook said he’s taking things “day by day” and will see how he feels at the end of the week. Everson Griffen (knee), Rashod Hill (ankle), Marcus Sherels (chest) and David Morgan (knee) were held out of Wednesday’s practice. — Courtney Cronin

NFC SOUTH

Atlanta Falcons

Any time Julio Jones pops up on the injury report, it raises some eyebrows. Well, Jones did not practice Wednesday while sidelined by a calf injury. There was no indication of Jones being injured in last week’s win over Carolina, so we’ll see how his status plays out. Jones joined running back Devonta Freeman (knee), defensive end Takk McKinley (groin), and defensive end Derrick Shelby (groin) as not practicing, as the Falcons continued preparation for the Saints. — Vaughan McClure

Carolina Panthers

The Panthers suffered two injuries in the secondary on Sunday, cornerback Donte Jackson a strained groin and safety Da’Norris Searcy a concussion. Replacing Searcy with rookie Rahsaan Gaulden or Colin Jones is easier than replacing Jackson, who has played well. The hope is that Jackson can practice on Thursday and be ready for the Bengals. — David Newton

New Orleans Saints

Starting nose tackle Tyeler Davison (foot) and linebacker Manti Te’o (knee) both missed practice Wednesday. It’s too early to determine if either is in jeopardy of missing Sunday’s game at Atlanta, but Davison was also held out last week. The Saints signed veteran defensive tackle Jay Bromley to add depth at the position. He had a solid summer performance in New Orleans before missing the 53-man cut. — Mike Triplett

Tampa Bay Buccaneers

Defensive tackle Beau Allen left Sunday’s game against the Eagles with a foot injury and did not return. The Bucs have not practiced yet for the week with a Monday night game on tap, so Allen’s status is up in the air; but, considering Vita Vea hasn’t returned from his calf injury yet and Mitch Unrein is on injured reserve with a concussion, the Bucs could be very thin along their interior defensive line. Safety Chris Conte also left Sunday’s game with a knee injury and did not return, leaving the Bucs’ young defensive backfield with even less experience. — Jenna Laine

NFC WEST

Arizona Cardinals

Cardinals wide receiver Larry Fitzgerald was limited Wednesday with a hamstring injury, but coach Steve Wilks said he expects Fitzgerald to play Sunday against Chicago. However, whether Fitzgerald plays or not may not make much of a difference if he’s ineffective with a sore hamstring. Fitzgerald was taken out of last week’s game against Los Angeles because of the injury; he said afterward that he could’ve continued to play, but wouldn’t have been effective. That issue may carry over into this weekend’s game — and potentially beyond — if the injury lingers. — Josh Weinfuss

Los Angeles Rams

Pro Bowl kicker Greg Zuerlein injured his groin during pregame warmups last week, and could be sidelined between three and six weeks, coach Sean McVay said. The Rams signed Sam Ficken, who also filled in for three games last season, to take over the position. Zuerlein’s absence means the Rams are likely to alter their offensive game plan in certain situations, given Zuerlein’s extraordinary ability to make field goals from 50-plus yards. “There is a little bit of a different mindset,” McVay said. “But by no means does that mean you don’t have confidence in Sam.” — Lindsey Thiry

San Francisco 49ers

Wide receiver Marquise Goodwin is still dealing with a deep thigh bruise that kept him out last week against Detroit, but he was able to participate on a limited basis in Wednesday’s practice. Goodwin’s absence has made it tough on the Niners passing game as the other pass catchers have struggled to separate against man coverage. He’s day to day this week, but the 49ers are hopeful he’ll be back Sunday against Kansas City. Safety Jaquiski Tartt is in a similar situation, as he deals with a shoulder injury that’s bothered him the past two weeks, and he did not practice Wednesday. — Nick Wagoner

Seattle Seahawks

The Seahawks could still be without receiver Doug Baldwin for at least another week, but All-Pro middle linebacker Bobby Wagner is expected to play Sunday against Dallas after missing the last game with a groin injury. While Seattle’s linebacker corps may not be fully intact yet — as K.J. Wright didn’t practice Wednesday — the team expects to have Wright’s replacement, newly signed Mychal Kendricks, available this week as he continues to appeal a suspension for his connection to insider trading. The team was pleased with how Kendricks (three tackles, sack, pass defensed) played Monday night after practicing with the team for only two days. He gives the Seahawks starting experience — at least while he’s still available — that was noticeably lacking in rookie Shaquem Griffin when he started in the opener for Wright. — Brady Henderson

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Breaking down the Indianapolis Colts’ 2018 draft class.

Round 1, No. 6 overall: Quenton Nelson, OG, Notre Dame

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My take: Nelson doesn’t play a headline-grabbing position, but he plays a position of significant need for the Colts. General manager Chris Ballard has repeatedly said they have to be able to control the line of scrimmage on both sides of the ball. It has been obvious over the years that the Colts have struggled on the offensive line, as they gave up an NFL-high 56 sacks last season, and poor play up front has played a factor in quarterback Andrew Luck missing 28 games over the past three seasons. The 3.7 yards per rush by the Colts ranked 28th in the NFL last season. Nelson excels in zone and gap-run schemes, according to coach Frank Reich. “He’s just instinctive,” Reich said. “He’s not only big and tough and strong and got all the football character, but when we started talking, we want instinctive football players that process it quickly. They find ways to be playmakers. We talk about it all the time: playmakers on the edge. We talk about playmakers up front, as well, and this guy is in that category.”

Trading back paid off: Ballard, based on the number of quarterbacks that could go in the top five, felt the Colts would still be able to get one of the eight premium players they believed were in the draft, while also acquiring two second-round picks and an additional second-rounder next year after swapping picks with the New York Jets. Nelson, Penn State running back Saquon Barkley and NC State pass-rusher Bradley Chubb were the top three of those eight players in the Colts’ eyes. Barkley went No. 2 to the Giants, and Chubb went to Denver at No. 5. Ballard got Nelson and the necessary additional picks to help speed up the rebuilding project ahead for the franchise. “There were a couple other guys in that group that we were perfectly content [with]. We think [they] are going to be really good players. But we had it narrowed down to about four guys that we thought would be instant starters for us, impact players and be Pro Bowl players eventually in time,” Ballard said.

Using first-rounders on the line: This is the second time in the past three drafts that the Colts have used their first-round pick on an offensive lineman. They selected center Ryan Kelly with the No. 18 pick in the 2016 draft. Kelly and Nelson join left tackle Anthony Castonzo, a 2011 first-rounder, as the foundation of the Colts’ offensive line. The Colts still have questions at the other guard position and at right tackle. Jack Mewhort and Matt Slauson are the early candidates for the other guard position. Mewhort is the younger of the two players, but he only has played a total of 15 games over the past two seasons due to injuries. Denzelle Good and Joe Haeg were the two primary right tackles last season. “When you’re good up front, offensively and defensively, it creates a dynamic, it creates an attitude throughout the whole team that you can win,” Reich said.
Darius Leonard is added to a Colts linebacker corps that needs a spark. Doug Buffington/Icon Sportswire
Round 2, No. 36: Darius Leonard, OLB, South Carolina State

My take: The Colts have so many needs on their roster that they really couldn’t go wrong with any position group at No. 36. They took Leonard over Boston College pass-rusher Harold Landry, who had 21.5 sacks in his final two college seasons. South Carolina State plays in the Football Championship Subdivision. Leonard planned to sign with Clemson out of high school, but he didn’t get the necessary test scores until after the signing period. He had 19 tackles against Clemson in a game in 2016. Leonard had 14 tackles in the Senior Bowl. Leonard had 394 tackles, 22 sacks and six interceptions in 43 career games.

How he fits: Snaps will potentially be there for Leonard because the Colts are in desperate need for help at linebacker. John Simon and Jabaal Sheard are moving to defensive end in the 4-3 defense under new coordinator Matt Eberflus. Leonard is an athletic linebacker capable of playing on third down because of his ability to drop back into coverage. Leonard joins a linebacker group that also features Antonio Morrison, Jeremiah George, Anthony Walker and Najee Goode.
Scott Donaldson/Icon Sportswire
Round 2, No. 37: Braden Smith, OG, Auburn

My take: Ballard is fully committed to improve the offensive line for quarterbacks Andrew Luck and Jacoby Brissett. Smith is the second offensive lineman selected by the Colts in their first three picks. They selected Notre Dame’s Quenton Nelson with the No. 6 pick on Thursday. One source told me that the Colts were tired of getting “bullied” on the offensive line. They gave up an NFL-high 56 sacks and 113 quarterback hits last season and have given up at least 32 sacks in five of the last six seasons.

How he fits: Depth and competition are the two important factors for the Colts on the offensive line. Smith said he also played some tackle while at Auburn, but his primary position was guard. Smith will compete with Jack Mewhort, Matt Slauson, Joe Haeg and Jeremy Vujnovich for a starting guard position. Nelson has the inside track for the starting left guard spot. Ballard has repeatedly said the Colts have to dominate the line of scrimmage on offense and defense if they expect to be able to have any kind of success.

Round 2, No. 52: Kemoko Turay, DE, Rutgers

My take: Pass-rusher has been a position of need for several years for the Colts. They haven’t had a legitimate one since Robert Mathis had 19.5 sacks in 2013. Turay had an impressive freshman season at Rutgers, recording 7.5 sacks. But consistency was an issue for Turay, who played standing up a lot. He had only seven sacks total in his final three college seasons. Part of the reason Turay was inconsistent was because he underwent two shoulder surgeries while in college.

How he fits: Turay will join a defensive-end rotation that features John Simon, Jabaal Sheard, Tarell Basham, Denico Autry and Henry Anderson. Matt Eberflus’ defensive scheme puts an emphasis on speed and getting up the field. The Colts want to be able to rotate bodies in so that they can wear down opponents by the fourth quarter. “I’m a hard worker,” Turay said. “I’m going to chase the ball 15 yards and make a play. They’re going to get a winner. I’m the new generation of [Denver’s] Von Miller.”

Round 2, No. 64: Tyquan Lewis, DE, Ohio State
The Colts took Ohio State’s Tyquan Lewis in hopes of bolstering the run defense and pass rush. Aaron Doster/USA Today Sports
My take: Ballard’s plan has become obvious as the draft has unfolded: build on the inside and work to the outside. Four of the Colts’ first five draft picks were on the offensive and defensive lines. The Colts were 26th in the NFL against the run (120.4 yards per game) and 31st in the league in sacks (25) last season. Lewis joins Turay on the defensive line. “I had some frustrating moments last year where I thought physically we didn’t match up, especially against teams in our division,” Ballard said. “These are young players and they’re going to have to grow and work and become NFL players. They all have talent.”

How he fits: Lewis is about to join a defensive line that will likely rotate players throughout the game. He had at least seven sacks and 9.5 tackles for loss in each of his final three seasons at Ohio State. The Colts don’t plan on having one key pass-rusher; they want to be able to have several so opponents can’t focus on just one player each week. “You win up front, you win when you rush, you win with speed and that’s how we’re going to play,” Ballard said. “We’re going to play in waves. The defensive line is always going to get the priority with us.”

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Prospect Profile: Nyheim HinesTake a look at NC State RB Nyheim Hines’ college highlights.
Round 4, No. 104: Nyheim Hines, RB, North Carolina State

My take: The Colts decided against re-signing veteran Frank Gore during the offseason as they make the transition to being younger in the backfield. Hines is joining a crowded backfield that already has Marlon Mack, Robert Turbin, Josh Ferguson and Christine Michael. There may end up being a primary back, but the Colts plan to rotate running backs depending on the situation of the game.

How he fits: Speed, speed and more speed. Hines’ 4.38 40-yard dash was the fastest among running backs during the combine. Hines fits in with coach Frank Reich’s offensive system of moving players around the field to force mismatches. Hines spent his first two seasons as a receiver at NC State before moving to running back last season. He describes his style of play as similar to Darren Sproles, Christian McCaffrey and Alvin Kamara. Hines rushed for 1,113 yards and 12 touchdowns last season at North Carolina State. Hines will also have the opportunity to be a return specialist for the Colts.

Round 5, No. 159: Daurice Fountain, WR, Northern Iowa
Wide receiver Daurice Fountain says that he will be the steal of the draft. Ken Murray/Icon Sportswire
My take: Receiver became a position of need after the Colts didn’t re-sign Donte Moncrief and Kamar Aiken. T.Y. Hilton and Chester Rogers are the only returning receivers that caught a pass for the Colts last season. K.J. Brent, Dres Anderson, Ryan Grant, Seantavius Jones, Krishawn Hogan, Justice Liggins and Kolby Listenbee, DeAndre Smelter and James Wright are the other receivers on the roster.

How he fits: The opportunity will be there for Fountain to get snaps. Hilton, Rogers and Grant are projected to be the top three receivers on the roster. Fountain doesn’t have great speed, but he’s known for his leaping ability. He only had four games of at least 100 yards receiving last season while playing in the Football Championship Subdivision. “My numbers don’t define how I play,” Fountain said. “I’m a big receiver, I can stretch the field and can play in the slot for mismatches.” Fountain said he’ll be the steal of the draft.

Round 5, No. 169: Jordan Wilkins, RB, Mississippi

My take: Wilkins is the second running back the Colts selected on the final day of the draft. They picked Hines in the fourth round to bring the running back total up to six players on the roster. It will be a tough training camp for snaps as the Colts work to figure out who will be in their running back rotation.

How he fits: Wilkins rushed for 1,011 yards and nine touchdowns while averaging 6.5 yards a carry last season at Ole Miss. He missed the 2016 season because of an academic suspension. Wilkins only had 32 receptions in three seasons in college. He’ll have to show he can catch the ball out of the backfield in Reich’s offensive system in order to get on the field.

Round 6, No. 185: Deon Cain, WR, Clemson

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Prospect Profile: Deon CainTake a look at Clemson WR Deon Cain’s college highlights.
My take: The Colts focused on the offensive and defensive line in the first two days of the draft and shifted to the skill positions on the final day. Cain is the second receiver — along with two running backs — selected on Day 3. Some people had Cain projected to be selected in the second or third round.

How he fits: Cain, who had 2,040 yards and 20 touchdowns in his three seasons at Clemson, was suspended for the College Football Playoff in 2015 for reportedly failing a drug test. He ran a 4.43 40-yard dash at the combine. Cain has a great combination of speed and size, but also earned a reputation for having too many drops while at Clemson. He said he was surprised that he was still on the board in the sixth round. “I was hearing because of off-the-field issues, production level,” Cain said. “I’m still a growing player, growing person. I learned from my mistakes made in college.”

Round 7, No. 221: Matthew Adams, LB, Houston

My take: The Colts finally added to their depth at inside linebacker with the addition of Adams. Inside linebacker can be looked at as one of their weaker positions. Antonio Morrison started there last season. The Colts signed Najee Goode, who spent the past five seasons in Philadelphia, and they also have Anthony Walker, a rookie last season, on the roster.
How he fits: Matthews only had 6.5 sacks in his career at Houston to go with 20.5 tackles for a loss. He led Houston in tackles (82) in 2016 and finished second (88) last season. Matthews started 22 games over his final two seasons with the Cougars.

Round 7, No. 235: Zaire Franklin, LB, Syracuse

My take: The Colts ended the draft with their second straight linebacker. By taking just two linebackers in the draft, the Colts don’t appear to be too worried about that position. Franklin, Adams, Najee Goode, Anthony Walker, Jeremiah George, Jermaine Grace, Antonio Morrison and Darnell Sankey are the inside linebackers on the roster. The Colts are shifting to a 4-3 defense next season.

How he fits: Franklin had 101 tackles during his junior season at Syracuse. Don’t expect Franklin to get after the quarterback, as he had only 8.5 sacks in his four years at the school. He’ll likely have to make an impact on special teams in order to make the roster.